Genetic Regulation of Signal Transduction and Metabolic Inflexibility
Grant number: 1184363 | Funding period: 2020 - 2022
Completed
Abstract
Understanding how our cells adapt to stress is vital to the study of all disease. A key feature of this adaption is modulating metabolism. However, based on their genetic profile, some individuals can’t effectively modulate metabolism resulting in diseases like diabetes. Very little is known about the genetics that regulate this metabolic adaption. This proposal will introduce a new approach to understand these interactions. Our overarching goal is to predict how and who will develop diabetes.